Children with cancer or hematopoietic cell transplant (HCT) frequently require ICU care. We conducted a retrospective cohort study using Healthcare Cost and Utilization Project's State Inpatient Databases from 21 U.S.
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December 2024
Apoptosis-regulating proteins from the B-cell lymphoma-2 (BCL-2) family are of continued interest as they represent promising targets for anti-cancer therapies. Myeloid cell leukemia-1 (MCL-1), which usually refers to the long isoform (MCL-1L) is frequently overexpressed in various types of cancer. However, MCL1 pre-mRNA can also undergo alternative splicing through exon skipping to yield the short isoform, MCL-1S.
View Article and Find Full Text PDFHealth care spending in the US reached $4.9 trillion and increased 7.5 percent in 2023, growing from a rate of 4.
View Article and Find Full Text PDFWe investigate the frequency response of narrow spectral holes in a doped crystal structure as a function of temperature below 1 K. We identify a particular regime in which this response significantly deviates from the expected two-phonon Raman scattering theory. Namely, near 290 mK, we observed a behavior exhibiting a temperature-dependent frequency shift of zero to first order.
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