Publications by authors named "M Harney"

Tumorigenesis can be modeled as a system of chaotic, nonlinear differential equations. From the analysis of these equations in state space, the onset of tumorigenesis can be predicted based on the status of parameters from the model.

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Article Synopsis
  • - The study focuses on the challenges of funding and patient access to combinations of on-patent therapies (CTs) in oncology, especially when they come from different manufacturers.
  • - Through literature review and interviews with experts across seven European countries, seven policy proposals were developed, emphasizing the necessity for coordinated approaches to affordability and funding.
  • - Key findings suggest that while major changes to health technology assessments may be unlikely, establishing bilateral discussions between manufacturers and payers and using usage-specific pricing strategies could improve the financial management of CTs across different countries.
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Current efforts to design supercharged protein assemblies have opened the door for the creation of substrates that could be used for drug delivery and as substrates for antiviral delivery mechanisms. We explore the potential for antiviral delivery with antisense RNAs that bind their phosphate backbone to the charge of an engineered protein oligomer, providing structural integrity to the RNA strand and adding possible steric effects to prevent reaction with unintended targets.

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Quantum entanglement has recently been demonstrated in macroscopic structures at the scale of microns. The densely packed chromatin that efficiently stores DNA strands may allow for gene expression through epigenetic modifiers within the close proximity of nearby strands and may also experience gene expression through quantum entanglement of epigenetic modifiers. Such an approach may have an evolutionary advantage in the densely packed realm of chromatin.

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Hearing healthcare outreach in developing countries is ill defined and inundated with sustainability challenges. One method to facilitate sustainable efforts is by training local personnel on certain aspects of hearing healthcare. The purpose of this descriptive study was to identify the challenges and successes of an audio-technician training program conducted in various regions throughout Guatemala.

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