Publications by authors named "M Hannig"
Probiotics as an adjunctive therapy in periodontitis treatment-reality or illusion-a clinical perspective.
NPJ Biofilms Microbiomes
December 2024
Periodontitis, a prevalent oral health issue, involves various microorganisms and clinical effects. This review examines probiotics as adjunctive therapy for periodontitis by analyzing forty clinical studies. Findings showed mixed results due to differences in study design, probiotic types, and clinical parameters; however, probiotics improved outcomes in severe cases.
View Article and Find Full Text PDFPlasmids are extrachromosomal DNA molecules in bacteria and archaea, playing critical roles in horizontal gene transfer, antibiotic resistance, and pathogenicity. Since its first release in 2018, our database on plasmids, PLSDB, has significantly grown and enhanced its content and scope. From 34 513 records contained in the 2021 version, PLSDB now hosts 72 360 entries.
View Article and Find Full Text PDFObjective: Ultrastructural analyses showed that during erosion under oral cavity conditions, dentin is infiltrated by a substrate morphologically similar to salivary proteins. This in-situ study aimed to investigate the presence of salivary proteins in demineralized dentin.
Methods: Bovine dentin specimens were attached to individual maxillary splints (n = 1 per subject and condition) and worn intraorally by four subjects for 1 min.
Article Synopsis
- Bacterial biofilms act as protective barriers, making it difficult for antibiotics to work effectively, but introducing oxygen can improve their effectiveness.
- This study investigates the use of oxygen-producing calcium peroxide nanoparticles (CaO NP) combined with tobramycin sulfate (Tob) on Pseudomonas aeruginosa biofilms, showing that the combination significantly enhances biofilm eradication compared to using Tob alone.
- In natural biofilms from human mouths, CaO NP increased the percentage of dead bacteria, and when combined with Tob, the dead bacteria percentage rose even further, demonstrating its potential benefits in real-life applications.
Introduction And Aims: With the increasing prevalence of dentin hypersensitivity, more and more desensitizing agents with tubule-occluding properties are advocated in the market. The aim of the present study was to investigate the deposition of these agents on the dentin surface under in-situ conditions.
Methods: Bovine dentin specimens were pretreated with phosphoric acid and fixed to individual upper splints that were carried by up to 2 subjects for 3 min to allow pellicle formation.