Publications by authors named "M Hamamci"
Article Synopsis
- * A study in Turkey examined the responses of 17 patients with solid tumors and NTRK fusions who received entrectinib, revealing a median age of 42 years and various types of cancer, with NTRK1 and NTRK3 being the most common gene rearrangements.
- * Results showed a 35.3% objective response rate with side effects leading to dosage reductions in four patients; the median overall survival was 20.8 months
Intragastric injection of botulinum toxin in the treatment of obesity: a single-center study.
Ther Adv Gastrointest Endosc
March 2024
Background: In recent years, various novel surgical and non-surgical therapeutic options have been developed for treating obesity. Due to its disputed success, intragastric botulinum toxin A (BTX-A) injection is still being debated.
Objectives: We aim to contribute to this controversial issue in the literature by sharing our center's findings regarding intragastric BTX-A injections in the treatment of obesity.
Purpose: Tuberous sclerosis complex (TSC) is a rare autosomal dominant genetic disorder that affects multiple organ systems. Mutations in the TSC1 and TSC2 genes result in the constitutive hyperactivation of the mammalian target of rapamycin (mTOR) pathway, contributing to the growth of benign tumors or hamartomas in various organs. Due to the implication of mTOR pathway dysregulation in the disease pathology, increasing evidence supports the use of mTOR inhibitors for treating multiple manifestations of TSC.
View Article and Find Full Text PDFBackground: In this study, we aimed to evaluate the association of lamina cribrosa thickness (LCT) and lamina cribrosa depth (LCD), as determined by spectral domain optical coherence tomography (SD-OCT), with visual evoked potentials (VEPs) in patients with multiple sclerosis (MS).
Materials And Methods: Patients enrolled in this prospective, cross-sectional study were divided into three groups. Group 1 consisted of 25 relapsing-remitting MS patients with VEP pathology in one or both eyes.
Article Synopsis
- Acute pancreatitis is increasingly common and severe among older adults, especially those over 80 years of age.
- A study analyzed 1150 patients with acute pancreatitis, finding that octogenarians had significantly higher rates of severe cases and complications compared to younger groups.
- Mortality rates were dramatically higher in older patients, with about 50% of those over 80 years old dying from the condition, unlike just 1.1% in the younger group.