Publications by authors named "M Hakan Akyildiz"
This interventional single-center prospective open-label study aims to evaluate the effects of a vegan diet, compared to a vegetarian and omnivorous diet, on metabolic parameters, insulin sensitivity, and liver and kidney steatosis in healthy adults. The study included 53 omnivorous participants aged 18-40 years, body-mass index 18-30 kg/m2, without any chronic disease, chronic medication use, active smoking, or significant alcohol consumption. All participants were omnivorous at baseline and selected to continue an omnivorous diet or transition to a vegetarian or vegan diet, with follow-up over six months.
View Article and Find Full Text PDFBackground: In countries with low rates of deceased donor solid organ transplantations, live-donor liver transplantation is the preferred definitive treatment for children and adults with end-stage liver disease. However, it is known that a remarkable number of potential living liver donors are rejected due to ABO incompatibility, suboptimal liver mass, or anatomical features. Paired exchange liver transplantation (PELT) practice emerged to overcome these obstacles.
View Article and Find Full Text PDFArticle Synopsis
- Midostaurin is the first targeted treatment for AML FLT3 and reduces mortality by 23% compared to standard chemotherapy, but it has side effects, especially gastrointestinal issues.
- A case was reported where a patient experienced acute pancreatitis symptoms after starting midostaurin, including abdominal pain and elevated enzyme levels.
- The patient was treated with IV hydration and anti-symptomatic care, recovering after four days, but drug-induced acute pancreatitis remains a rare and complicated diagnosis without established links to midostaurin despite various potential mechanisms.
Article Synopsis
- The study aimed to adapt the Vestibular Migraine Patient Assessment Tool and Handicap Inventory (VM-PATHI) for use in Turkey due to a lack of diagnostic tools for vestibular migraine.
- Researchers conducted pilot studies and various analyses (EFA, CFA) to validate the tool's language, structure, and reliability.
- Results showed strong validity and reliability of the VM-PATHI, making it an effective tool for assessing vestibular migraine in the Turkish population.
Objective: To evaluate the effects of different attachment configurations with and without buccal root torque on expansion movements achieved with aligners through finite element analysis (FEA).
Methods: FEA modelling was done with 0.25 mm buccal expansion force application to the maxillary molars with different attachment configurations: Eight models were tested (1) no attachment (NA), (2) horizontal attachment (HA), (3) gingivally beveled horizontal attachment (GHA), and (4) occlusally beveled horizontal attachment (OHA), as well as models with 6buccal root torque, (5) no attachment (TNA), (6) horizontal attachment (THA), (7) gingivally beveled horizontal attachment (TGHA), and (8) occlusally beveled horizontal attachment (TOHA).