Publications by authors named "M Hagiya"
Article Synopsis
- * A particular case highlighted involved PVT along with paroxysmal atrial fibrillation, where the only symptoms presented were transient ischemic attacks.
- * Diagnosis of PVT was confirmed using contrast-enhanced computed tomography (CT), which revealed a thrombus, and after changing the patient's anticoagulant medication, the thrombus resolved in 5 months, showing CT's effectiveness for diagnosis and monitoring.
Transformation of L., a recalcitrant species, using a T-DNA construct carrying two genes.
Plant Biotechnol (Tokyo)
March 2023
A binary vector carrying two () genes, and , under the control of a chemical-inducible expression system, worked in the transformation in . , a recalcitrant species of . The resulting transformants exhibited improved culture performance in regeneration from leaf segments and suspended cells.
View Article and Find Full Text PDFAccelerating the Finite-Element Method for Reaction-Diffusion Simulations on GPUs with CUDA.
Micromachines (Basel)
September 2020
DNA nanotechnology offers a fine control over biochemistry by programming chemical reactions in DNA templates. Coupled to microfluidics, it has enabled DNA-based reaction-diffusion microsystems with advanced spatio-temporal dynamics such as traveling waves. The Finite Element Method (FEM) is a standard tool to simulate the physics of such systems where boundary conditions play a crucial role.
View Article and Find Full Text PDFBackground: Corneal endothelial cell (CEC) disorders, such as Fuchs's endothelial corneal dystrophy, induce abnormal corneal hydration and result in corneal haziness and vision loss known as bullous keratopathy. We investigated whether injection of cultured human CECs supplemented with a rho-associated protein kinase (ROCK) inhibitor into the anterior chamber could increase CEC density.
Methods: We performed an uncontrolled, single-group study involving 11 persons who had received a diagnosis of bullous keratopathy and had no detectable CECs.
Article Synopsis
- The corneal endothelium is crucial for maintaining corneal transparency, and its dysfunction can lead to significant vision issues.
- Tissue engineering, specifically cell-based therapies using monkey and human corneal endothelial cells, shows promise as a less invasive alternative to traditional corneal transplants.
- The incorporation of a ROCK inhibitor enhances the engraftment of these cells, suggesting potential for effective treatment of corneal endothelial dysfunction in future clinical applications.