Publications by authors named "M Hadj Taieb"

Pleomorphic xanthoastrocytoma (PXA) is a rare low-grade glial neoplasm of the central nervous system accounting for less than 1% of all astrocytomas. Similar to other gliomas, it can rarely arise from glial nests in the meninges, manifesting as an extra-axial mass mimicking a meningioma. Extra axial PXA is an extremely rare entity.

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Psoriasis is a chronic, immune-mediated, hyperproliferative skin disease. Etiopathogenesis of psoriasis is not well understood. Plexin B2 was found to have effects on CD100-mediated T-cell morphology and expressed in the immune system.

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Article Synopsis
  • Psoriasis is an autoimmune disease affecting skin and joints, and TWEAK is a cytokine linked to various conditions.
  • A study measured serum TWEAK levels in 40 psoriasis patients pre- and post-therapy with narrowband UVB or methotrexate, comparing results with 20 healthy controls.
  • Results showed greater improvement in the PASI score for the methotrexate group (90%) compared to the UVB group (60%), with TWEAK levels significantly decreasing in both treatment groups, indicating its potential as a biomarker for psoriasis severity and treatment response.
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Objectives: Alterations in tryptophan (Trp) metabolism have been reported in inflammatory diseases, including rheumatoid arthritis (RA). However, understanding whether these alterations participate in RA development and can be considered putative therapeutic targets remains undetermined.In this study, we combined quantitative Trp metabolomics in the serum from patients with RA and corrective administration of a recombinant enzyme in experimental arthritis to address this question.

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Background: In the entire world, acne vulgaris (AV) is the most prevalent skin condition. Approximately 9.4% of people worldwide have acne vulgaris.

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