Discordant Diagnosis of Coronary Microvascular Dysfunction by Microvascular Resistance Reserve: Transthoracic Doppler Echocardiography vs Bolus Thermodilution Method.

Background: Epicardial stenosis and coronary microvascular dysfunction (CMD) may coexist in patients with chronic coronary syndrome (CCS). Microvascular resistance reserve (MRR) has been demonstrated to be a valid cross-modality metric using continuous saline infusion thermodilution and intracoronary Doppler flow velocity methods. This study aimed to investigate the prevalence and diagnostic concordance of CMD defined by MRR using two methods-stress transthoracic Doppler echocardiography (S-TDE) and the invasive bolus thermodilution method (B-Thermo)-in patients with functionally significant epicardial stenosis.

Prognostic Value of Endogenous-Type Coronary Microvascular Dysfunction After Elective Percutaneous Coronary Intervention.

Background: Global coronary flow reserve (G-CFR) impairment represents coronary microvascular dysfunction (CMD) and correlates with poor prognosis. Hyperemic coronary flow is reduced in conventional CMD, but normal or mildly reduced with elevated resting flow in endogenous-type CMD (E-CMD). This retrospective study assessed the prognostic value of post-percutaneous coronary intervention (PCI) CMD, focusing on E-CMD.

Inversion of circularly polarized luminescence by electric current flow during transition.

The development of chiral compounds exhibiting circularly polarized luminescence (CPL) has advanced remarkably in recent years. Designing CPL-active compounds requires an understanding of the electric transition dipole moment () and the magnetic transition dipole moment () in the excited state. However, while the direction and magnitude of can, to some extent, be visually inferred from chemical structures, remains elusive, posing challenges for direct predictions based on structural information.

Dithienonaphthobisthiadiazole synthesized by thienannulation of electron-deficient rings: an acceptor building unit for high-performance π-conjugated polymers.

The development of building units for π-conjugated polymers is a driving force in advancing the field of organic electronics. In this study, we designed and synthesized dithienonaphthobisthiadiazole (TNT) as a thiophene-fused acceptor (A) building unit and two TNT-based π-conjugated polymers named PTNT2T and PTNT1-F. We found that the microwave-assisted thiophene annulation reaction (thienannulation) of arylethynylated naphthobisthiadiazole (NTz) C-H functionalization effectively produced TNT moieties.