Didemnins as marine-derived anticancer agents: mechanistic insights and clinical potential.

Didemnins, a class of cyclic depsipeptides derived from marine organisms exhibit notable anticancer properties. Among them, Didemnin B has been extensively researched for its strong antitumor activity and progression to clinical trials. Nonetheless, its clinical application has been impeded by challenges like poor bioavailability and dose-limiting toxicity.

An Adaptive Spatio-Temporal Traffic Flow Prediction Using Self-Attention and Multi-Graph Networks.

Traffic flow prediction is a pivotal element in Intelligent Transportation Systems (ITSs) that provides significant opportunities for real-world applications. Capturing complex and dynamic spatio-temporal patterns within traffic data remains a significant challenge for traffic flow prediction. Different approaches to effectively modeling complex spatio-temporal correlations within traffic data have been proposed.

Recent Advancements in Localization Technologies for Wireless Capsule Endoscopy: A Technical Review.

Conventional endoscopy is limited in its ability to examine the small bowel and perform long-term monitoring due to the risk of infection and tissue perforation. Wireless Capsule Endoscopy (WCE) is a painless and non-invasive method of examining the body's internal organs using a small camera that is swallowed like a pill. The existing active locomotion technologies do not have a practical localization system to control the capsule's movement within the body.

Real-Time PPG-Based Biometric Identification: Advancing Security with 2D Gram Matrices and Deep Learning Models.

The integration of liveness detection into biometric systems is crucial for countering spoofing attacks and enhancing security. This study investigates the efficacy of photoplethysmography (PPG) signals, which offer distinct advantages over traditional biometric techniques. PPG signals are non-invasive, inherently contain liveness information that is highly resistant to spoofing, and are cost-efficient, making them a superior alternative for biometric authentication.

Nitric Oxide Pre-Treatment Advances Bulblet Dormancy Release by Mediating Metabolic Changes in .

The lily is a globally popular cut flower, and managing dormancy in lily bulblets is essential for continuous, year-round production. While nitric oxide (NO) has been shown to influence seed dormancy and germination, its role in dormancy release in lilies was previously unconfirmed. In this study, we investigated the effects of NO on dormancy release in lily bulblets using SNP and c-PTIO.