Publications by authors named "M HAVLIK"

Article Synopsis
  • The study examines the chiral properties of nickel(II) complexes derived from various porphyrin derivatives with substituted phenyl groups.
  • Investigations into the enantioseparation of racemic mixtures were conducted using high-performance liquid chromatography (HPLC) techniques.
  • The purity and configurations of the isolated enantiomers were confirmed through HPLC, UV-Vis spectroscopy, and TDDFT calculations, revealing specific maximum molar ellipticity values.
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In this work, two stilbene derivatives with different substituents on the phenolic core (phenyl and dimethoxyphenyl) were prepared. The fluorosolvatochromic response of their -propylated derivatives was studied in a solution of twelve different solvents using UV-Vis absorption and fluorescence emission spectra. Both stilbazolium dyes showed a significant negative solvatochromic effect, with a hypsochromic shift in the visible absorption band of approximately 232 nm and 265 nm for phenyl and the dimethoxyphenyl derivative, respectively, when the solvent was changed from water to pyridine.

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Neuroblastoma represents 8-10 % of all malignant tumors in childhood and is responsible for 15 % of cancer deaths in the pediatric population. Aggressive neuroblastomas are often resistant to chemotherapy. Canonically, neuroblastomas can be classified according to the MYCN (N-myc proto-oncogene protein) gene amplification, a common marker of tumor aggressiveness and poor prognosis.

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Oceans are crucial to human survival, providing natural resources and most of the global oxygen supply, and are responsible for a large portion of worldwide economic development. Although it is widely considered a silent world, the sea is filled with natural sounds generated by marine life and geological processes. Man-made underwater sounds, such as active sonars, maritime traffic, and offshore oil and mineral exploration, have significantly affected underwater soundscapes and species.

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Article Synopsis
  • Conscious experience is a complex issue in neuroscience, with current studies struggling to pinpoint the essential neural events that lead to consciousness.
  • The existing research is mainly speculative and relies heavily on observing correlations rather than understanding the underlying mechanisms.
  • New brain stimulation techniques, like geodesic transcranial electric neuromodulation, may offer an alternative method focused on causation that could advance our understanding of how consciousness operates.
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