Publications by authors named "M HAMAZAKI"
Global methylation levels differ in in vitro- and in vivo-developed embryos. Follicular fluid (FF) contains extracellular vesicles (EVs) containing miRNAs that affect embryonic development. Here, we examined our hypothesis that components in FF affect global DNA methylation and embryonic development.
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- - The study examined how low levels of ethanol (0.1% and 0.2%) impact the maturation and development of bovine oocytes, focusing on metrics like nuclear maturation rates, mitochondrial DNA levels, ATP content, and lipid content.
- - Results showed that 0.1% ethanol improved mitochondrial function and energy usage in cumulus-oocyte complexes (COCs), while 0.2% ethanol enhanced ATP content and blastulation rates but reduced lipid levels.
- - RNA sequencing analysis indicated that exposure to ethanol altered gene expression related to various metabolic pathways, suggesting that even low ethanol concentrations significantly impact oocyte metabolism and embryo development.
Background And Aim: Double-balloon endoscopic retrograde cholangiography (DBERC) is a valuable procedure for patients with altered gastrointestinal anatomy. Nonetheless, it is time-consuming and burdensome for both patients and endoscopists, partly because route selection in the reconstructed bowel with complicating loop is challenging. Carbon dioxide insufflation enterography is reportedly useful for route selection in the blind loop.
View Article and Find Full Text PDFBackground: Fecal microbiota transplantation (FMT) is a potential treatment for irritable bowel syndrome (IBS), but its efficacy in Japanese IBS patients is unknown. This study aimed to evaluate the efficacy, side effects, and microbiome changes following FMT in Japanese IBS patients.
Methods: Seventeen Japanese patients with refractory IBS received FMT (4 donors) under colonoscopy.