Publications by authors named "M H Schenone"

Objectives: Fetal growth restriction (FGR) is commonly associated with placental dysfunction, increasing perinatal morbidity and mortality. Visualizing placental vessels in utero would be advantageous for identifying functional FGR cause and determining proper management strategies. We aimed to utilize high-sensitivity ultrasound microvessel imaging (HUMI) for quantifying placental vessel density (VD) in pregnancies diagnosed with FGR.

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Article Synopsis
  • The study investigates the impact of adequate empirical combination therapy (AECT) on 30-day mortality rates in septic shock patients infected with Pseudomonas aeruginosa.
  • Of 98 patients analyzed, those receiving AECT had a significantly lower mortality rate (25%) compared to those on adequate empirical monotherapy (AEMT) (56.8%), indicating AECT may enhance survival.
  • The findings suggest transitioning to a single effective antibiotic after confirming susceptibility is safe, highlighting the need for further research to validate these results.
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The fetal sheep model has been widely used in fetal therapy research. However, there is a significant degree of variability among published normal values. Our study aimed to evaluate the literature available on normal values for hemodynamics, blood gases, and acid-base status in the sheep fetus and to determine the best possible estimation of such physiologic values.

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Introduction: Congenital hydrocephalus often results in irreversible and severe damage to the brain despite postnatal interventions. The potential for prenatal intervention to mitigate these deleterious effects underscores the importance of a suitable animal model. We aimed assess the results of an ultrasound-guided transuterine approach to replicate the BioGlue injection fetal hydrocephalus model.

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