Prevalence of HI antibody titer against rubella virus to determine the effect of mass vaccination in Tehran.

Background: Rubella is an infectious viral disease, has a worldwide distribution and is normally a mild childhood disease. Infection during early pregnancy may cause fetal death or congenital rubella syndrome. The highest risk of CRS is found in countries with high susceptibility rates among women of childbearing age.

Study of a polymerase chain reaction-based method for detection of herpes simplex virus type 1 DNA among Iranian patients with ocular herpetic keratitis infection.

Purpose: To study the presence of the herpes simplex virus type 1 (HSV-1) glycoprotein D gene in tear films of Iranian patients with herpetic keratitis.

Methods: Twenty-five tear film and eye swab specimens from 25 herpetic keratitis patients and 10 specimens from 10 healthy volunteers were collected in the Farabi Eye Hospital, Tehran, Iran. HSV-1 DNA was detected by using the nested polymerase chain reaction (nPCR) method.

Seroprevalence of neutralizing antibodies to measles virus in a vaccinated population in Iran, 1998.

Measles is an acute highly infectious viral disease. Although live attenuated vaccine is used throughout the world, outbreaks of disease still occur in many countries including Iran. In this cross-sectional study, by implementing a viral neutralization test and cell culture techniques, the seroprevalence of neutralizing anti-measles antibodies was assessed.

Development of an enzyme-linked immunosorbent assay for immunoglobulin M antibodies against measles virus.

Measles is a highly contagious respiratory virus infection, with typical clinical symptoms including maculopapular rash, fever, cough, coryza, and conjunctivitis. Despite implementation of widespread vaccination programs throughout the world, the rates of global morbidity and mortality are still considerable. This study was performed to design a reliable indirect enzyme-linked immunosorbent assay (ELISA) to measure measles-specific immunoglobulin M (IgM).

Incidence of enteric adenovirus gastroenteritis in Iranian children.

Background: Enteric adenoviruses, i.e. adenovirus 40 (Ad40) and adenovirus 41 (Ad41), have been shown to be a substantial cause of pediatric gastroenteritis in various parts of the world, but no data are available for Iran.