Fully automated coronary artery calcium score and risk categorization from chest CT using deep learning and multiorgan segmentation: A validation study from National Lung Screening Trial (NLST).

Background: The National Lung Screening Trial (NLST) has shown that screening with low dose CT in high-risk population was associated with reduction in lung cancer mortality. These patients are also at high risk of coronary artery disease, and we used deep learning model to automatically detect, quantify and perform risk categorisation of coronary artery calcification score (CACS) from non-ECG gated Chest CT scans.

Materials And Methods: Automated calcium quantification was performed using a neural network based on Mask regions with convolutional neural networks (R-CNN) for multiorgan segmentation.

Frequency and characteristics of gnathic dense bone islands in a paediatric population residing in Chandigarh, India: a cross-sectional radiographic study.

Aim: To determine the frequency and characteristics of Dense Bone Islands (DBIs) in a paediatric population residing in Chandigarh, India.

Methodology: A total of 3614 orthopantomographs (OPG) of children between the age group of 6-18 years were collected from the database of patients who underwent panoramic radiography for routine dental treatment during the period of 2018-2020. The shape, location of the lesion, and relationship of the Dense Bone Island with the tooth were identified.

Salmonella Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol.

Salmonella enterica serotype Typhimurium (Salmonella) resides and multiplies intracellularly in cholesterol-rich compartments called Salmonella-containing vacuoles (SCVs) with actin-rich tubular extensions known as Salmonella-induced filaments (SIFs). SCV maturation depends on host-derived cholesterol, but the transport mechanism of low-density lipoprotein (LDL)-derived cholesterol to SCVs remains unclear. Here we find that peroxisomes are recruited to SCVs and function as pro-bacterial organelle.

Detection of Rotavirus, Norovirus, and Astrovirus Causing Acute Diarrhoea in Children by Multiplex PCR in a Tertiary Care Hospital.

Objective: To evaluate the use of a multiplex real-time polymerase chain reaction (RT-PCR) test in detecting three viruses namely Rotavirus, Norovirus (genotypes 1 and 2), and Astrovirus that cause gastroenteritis in children under the age of five years.

Study Design: A cross-sectional study. Place and Duration of the Study: Department of Virology, Armed Forces Institute of Pathology (AFIP), Rawalpindi, Pakistan, from January to July 2023.

Assessment of Dental Anxiety in a Young Population of the North Indian City of Lucknow.

Introduction: Dental anxiety is a common fear, especially among younger age groups, and it can prevent individuals from seeking necessary dental treatment. Effective communication between dental professionals and young adults is crucial to address this issue. However, factors such as past experiences, peer influences, and coping strategies can impact a young adult's anxiety in a dental setting.