Publications by authors named "M H Mankani"
Article Synopsis
- Individualized guided selection of antiplatelet therapy, which uses genetic and platelet function testing, has the potential to improve outcomes for patients undergoing percutaneous coronary intervention (PCI) compared to standard therapy.
- A systematic review pooled data from 11 clinical trials involving 18,465 patients and found that guided therapy significantly reduced major adverse cardiovascular events (MACE), heart attacks (MI), stent thrombosis (ST), strokes, and minor bleeding.
- The results suggest that implementing genetic and platelet function testing can lead to better antiplatelet therapy choices for patients, ultimately enhancing their overall health outcomes.
Autologous transplantation of human bone marrow stromal cells (BMSCs) has been successfully used for bone reconstruction. However, in order to advance this approach into the mainstream of bone tissue engineering, the conditions for BMSC cultivation and transplantation must be optimized. In a recent report, cultivation with dexamethasone (Dex) significantly increased bone formation by human BMSCs in vivo.
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