Publications by authors named "M H M E Anten"
Purpose: Meningiomas classified as grade 2-3 according to the World Health Organisation (WHO) require combined surgery and in most cases radiotherapy (RT). Their initial management was evaluated using the Dutch Brain Tumour Registry.
Methods: The study included 393 patients aged ≥ 18 years with newly diagnosed meningioma WHO grade 2-3 between 2016 and 2021.
Glioblastoma (GBM) continues to exhibit a discouraging survival rate despite extensive research into new treatments. One factor contributing to its poor prognosis is the tumor's immunosuppressive microenvironment, in which the kynurenine pathway (KP) plays a significant role. This study aimed to explore how KP impacts the survival of newly diagnosed GBM patients.
View Article and Find Full Text PDFBackground: This study aimed to assess the performance of currently available risk calculators in a cohort of patients with malignant peripheral nerve sheath tumors (MPNST) and to create an MPNST-specific prognostic model including type-specific predictors for overall survival (OS).
Methods: This is a retrospective multicenter cohort study of patients with MPNST from 11 secondary or tertiary centers in The Netherlands, Italy and the United States of America. All patients diagnosed with primary MPNST who underwent macroscopically complete surgical resection from 2000 to 2019 were included in this study.
Article Synopsis
- Glioblastoma (GBM) treatment typically uses large radiotherapy margins, but this study evaluates the safety of reducing the clinical target volume (CTV) margin from 20 mm to 15 mm around the tumor to minimize radiation exposure to healthy brain tissue.* -
- The analysis involved comparing two patient groups treated with different CTV margins, revealing significant reductions in volume and radiation dose to surrounding organs, while maintaining similar recurrence patterns and survival outcomes.* -
- The findings suggest that a 15 mm CTV margin in GBM patients undergoing chemoradiation is safe and may reduce treatment-related toxicity without compromising effectiveness.*
Background: Data on the incidence and clinical relevance of gallstones in patients with suspected acute alcoholic pancreatitis are lacking and are essential to minimize the risk of recurrent acute pancreatitis. The aim of this study was to assess the incidence of gallstones and the associated rate of recurrent acute pancreatitis in patients with presumed acute alcoholic pancreatitis.
Methods: Between 2008 and 2019, 23 hospitals prospectively enrolled patients with acute pancreatitis.