The Association between All-cause Mortality and Obstructive Sleep Apnea in Adults: A U-Shaped Curve.

Rationale And Objectives: The relationship between Sleep Apnea (SA) and mortality remains a topic of debate. We explored the relationship between the severity of SA and mortality and the effect of age on this association.

Methods: Using a Veterans' database, we extracted the apnea-hypopnea index (AHI) from physician interpretation of sleep studies, by developing a Natural Language Processing (NLP) pipeline (with 944 manually annotated notes) which achieved more than 85% accuracy.

Sex-specific associations between habitual snoring and cancer prevalence: insights from a US Cohort Study.

Study Objectives: To investigate the sex-specific association between habitual snoring and overall cancer prevalence and subtypes, and to examine the influence of age, body mass index (BMI), and sleep duration on this association.

Methods: This study utilized data from the National Health and Nutrition Examination Survey cycles between 2005 and 2020 and included 15 892 participants aged 18 and over. We employed inverse probability of treatment weighting based on propensity scores to adjust for confounders when comparing the prevalence of cancer between habitual snorers and non-habitual snorers for each sex and cancer type.

Age modulates the predictive value of self-reported sleepiness for all-cause mortality risk: insights from a comprehensive national database of veterans.

Study Objectives: Excessive daytime sleepiness is prevalent and overwhelmingly stems from disturbed sleep. We hypothesized that age modulates the association between excessive daytime sleepiness and increased all-cause mortality.

Methods: We utilized the Veterans' Health Administration data from 1999-2022.