Estimating railway track curvature using gyroscope and GPS sensors.

The horizontal curvature of railway tracks plays a significant role in vehicle‒track dynamics, and accurate knowledge of the track curvature is essential for vehicle operators to fully understand the running behavior of vehicles. However, it is generally difficult for wagon operators or researchers to obtain track geometry information due to confidential reasons. Using sensors installed on wagons is an alternative to estimate the track curvature.

Impact of Different Mediastinal Staging Modalities on Target Volume Delineation in Locally Advanced Non-Small-Cell Lung Cancer: A Secondary Analysis of the Multicenter Randomized PET-Plan Trial.

Purpose: To evaluate the role of different invasive and non-invasive mediastinal staging methods in patients with locally advanced non-small-cell lung cancer (NSCLC) treated with definitive chemoradiotherapy in the prospective XXX trial (XXX; NCTXXX) and to evaluate the impact of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and mediastinoscopy on target volume definition.

Methods: Patients treated per-protocol (n = 172), all receiving isotoxically dose-escalated chemoradiotherapy, were included in this unplanned secondary analysis. Radiation treatment planning was based on an F-FDG PET/CT targeting all CT positive lymph nodes (i.

Protocol for a national randomized controlled trial evaluating the Opioid Rapid Response System for overdose death prevention.

Introduction: Deaths of opioid overdose are a serious public health concern throughout the U.S., transcending geographical and demographic categories.

Machine learning based on blood test biomarkers predicts fast progression in advanced NSCLC patients treated with immunotherapy.

Objective: Fast progression (FP) represents a desperate situation for advanced non-small cell lung cancer (NSCLC) patients undergoing immune checkpoint inhibitor therapy. We aimed to develop a predictive framework based on machine learning (ML) methods to identify FP in advanced NSCLC patients using blood test biomarkers.

Methods And Analysis: We extracted data of 1546 atezolizumab-treated patients from four multicentre clinical trials.

Seroprevalence of dengue, Zika, and chikungunya in São Sebastião, Brazil (2020-2021): a population-based survey.

Background: Urban arboviruses pose a significant global burden, particularly in tropical regions like Brazil. São Sebastião, a lower-middle-class urban area just 26 km from the Brazilian capital, is an endemic area for dengue. However, asymptomatic cases may obscure the actual extent of the disease.