Therapeutic efficacy of artesunate-amodiaquine and artemether-lumefantrine for the treatment of uncomplicated falciparum malaria in Chad: clinical and genetic surveillance.

Background: Artesunate-amodiaquine (AS-AQ) and artemether-lumefantrine (AL) are the currently recommended first-and second-line therapies for uncomplicated Plasmodium falciparum infections in Chad. This study assessed the efficacy of these artemisinin-based combinations, proportion of day 3 positive patients, proportions of molecular markers associated with P. falciparum resistance to anti-malarial drugs and variable performance of HRP2-based malaria rapid diagnostic tests (RDTs).

[Episcleral single injection anesthesia in the caruncle for cataract surgery: report of 350 cases].

Episcleral single injection anesthesia in the caruncle ovoïds the rare but potentially dangerous complications and incidents of classic local anesthesia. Excellent motor and sensory block is obtained with a single injection in the anatomic marks are well defined. We have practiced this technique since February 1999 for cataract surgery in 350 cases.

[Occlusion of the central retinal vein in a 6-month pregnant woman].

The authors report the case of 27-year old woman who was 6 months pregnant (second pregnancy, first parity) and presented an occlusion of the central retinal vein. The etiological investigation revealed impaired fibrinolysis after venous stasis. The clinical course including evolution and therapy was stressed.