Publications by authors named "M H Fraser"

Characterizing biodiversity using environmental DNA (eDNA) represents a paradigm shift in our capacity for biomonitoring complex environments, both aquatic and terrestrial. However, eDNA biomonitoring is limited by biases toward certain species and the low taxonomic resolution of current metabarcoding approaches. Shotgun metagenomics of eDNA enables the collection of whole ecosystem data by sequencing all molecules present, allowing characterization and identification.

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Background: Multiple myeloma (MM) is a hematological malignancy characterized by the clonal proliferation of malignant plasma cells within the bone marrow. The disease's complexity is underpinned by a variety of genetic and molecular abnormalities that drive its progression.

Methods: This review was conducted through a state-of-The-art literature search, primarily utilizing PubMed to gather peer-reviewed articles.

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Lower urinary tract dysfunction (LUTD) increases with aging. Ensuing symptoms including incontinence greatly impact quality of life, isolation, depression, and nursing home admission. The aging bladder is hypothesized to be central to this decline, however, it remains difficult to pinpoint a singular strong driver of aging-related bladder dysfunction.

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Article Synopsis
  • Core loss spectroscopies offer detailed insights into redox processes in Li-ion battery cathodes, necessitating precise interpretation of their spectral features, particularly the oxygen K-edge spectra of lithium transition-metal oxides (LiMO).
  • Using density-functional theory (DFT), three exchange-correlation functionals were applied to simulate the spectra, with rSCAN showing a better alignment with experimental data compared to PBE and PBE +, especially for energies near the main edge.
  • The study demonstrates that DFT can effectively link experimental spectroscopic signatures to theoretical models, revealing the impact of structural distortions, chemical composition, and magnetism on the differentiation of materials with similar structures and magnetic states.
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