Prefrontal cortex stimulation normalizes deficient adaptive learning from outcome contingencies in low mood.

Depression and anxiety are associated with deficits in adjusting learning behaviour to changing outcome contingencies. This is likely to drive and maintain symptoms, for instance, by perpetuating negative biases or a sense of uncontrollability. Normalising such deficits in adaptive learning might therefore be a novel treatment target for affective disorders.

Successful Aging across Middle vs High-Income Countries: An Analysis of the Role of eHealth Literacy Associated with Loneliness and Wellbeing.

Background And Objectives: "Successful aging" concerns the process of growing older while maintaining physical, cognitive, and social wellbeing, emphasizing independence for overall satisfaction and quality of life. We investigate the impact of e-health literacy on reducing loneliness and sustaining wellbeing during the pandemic, comparing middle- and high-income countries.

Research Design And Methods: Online surveys were conducted between April 4, 2020, and September 30, 2021, collecting responses (N=2091) from medium- and high-income countries in Europe, Asia, and North America.

Nurse academics' attitudes towards technology: A mixed methods study.

Background: Technology is being increasing used in education of nursing students. Nurse academics act both as gatekeepers to technology within their classes and as an example of technology attitudes. Therefore, understanding the attitude of academics to technology from the academic's perspective is necessary to understand barriers and enablers of technology engagement.

Direct serotonin release in humans shapes aversive learning and inhibition.

The role of serotonin in human behaviour is informed by approaches which allow in vivo modification of synaptic serotonin. However, characterising the effects of increased serotonin signalling in human models of behaviour is challenging given the limitations of available experimental probes, notably selective serotonin reuptake inhibitors. Here we use a now-accessible approach to directly increase synaptic serotonin in humans (a selective serotonin releasing agent) and examine its influence on domains of behaviour historically considered core functions of serotonin.