Publications by authors named "M H Criqui"

Background: Oxidized phospholipids (OxPLs) are carried by apolipoprotein B-100-containing lipoproteins (OxPL-apoB) including lipoprotein(a) (Lp[a]). Both OxPL-apoB and Lp(a) have been associated with calcific aortic valve disease (CAVD).

Objectives: This study aimed to evaluate the associations between OxPL-apoB, Lp(a) and the prevalence, incidence, and progression of CAVD.

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Article Synopsis
  • The study investigates the role of dietary flavonoids in reducing atherosclerosis-related cardiovascular diseases by analyzing data from 5,599 participants in the MESA study.
  • Researchers examined the link between flavonoid intake and various subclinical markers of atherosclerosis, considering factors like time, sex, race/ethnicity, and smoking status.
  • Results showed that higher flavonoid intake was associated with significantly lower odds of having poorer ankle-brachial indices and carotid plaques, suggesting the potential protective effects of flavonoids on cardiovascular health.
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Background: Mitochondrial abnormalities exist in lower-extremity peripheral artery disease (PAD), yet the association of the ankle-brachial index (ABI) with mitochondrial respiration in gastrocnemius muscle is unknown. The association of gastrocnemius mitochondrial respiration with 6-minute walk distance in PAD is unknown. This objective of this study was to describe associations of the ABI with mitochondrial respiratory function in gastrocnemius muscle biopsies and associations of gastrocnemius mitochondrial respirometry with 6-minute walk distance in people with and without PAD.

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