Publications by authors named "M H Augenbraun"

Article Synopsis
  • A study investigated long-term body weight changes in people with HIV (PWH) who switched to antiretroviral therapies containing integrase strand-transfer inhibitors (INSTIs), comparing them with those on non-INSTI therapies and people without HIV (PWOH).
  • The analysis included 3464 participants and revealed that women experienced significantly greater weight gain and increases in hip and thigh circumference after switching to INSTIs compared to men, with women gaining +3.0 kg and men +1.8 kg over 5 years.
  • The findings suggest a 2-fold higher weight change in women versus men following the switch to INSTIs, although the long-term health implications of this difference are still uncertain.
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Article Synopsis
  • Host metabolic issues, particularly in tryptophan metabolism, are linked to the severity of COVID-19 and long COVID symptoms.
  • People with HIV also experience similar metabolic problems, raising questions about their risk for severe COVID-19 outcomes.
  • Research on samples from people living with HIV indicates that certain metabolic changes may predict higher risks for severe COVID-19 and long COVID, suggesting a need for further study.
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Unlabelled: Multi-drug resistance in the post COVID-19 world is a growing concern. The objective of this study was to describe temporal trends and explore independent risk factors for the isolation of multi-drug resistant (MDR)

Methods: This was a retrospective case-control study of patients with isolates recovered from January 2019 to December 2020. MDR was defined as non-susceptibility to at least one agent in three or more anti-pseudomonal antimicrobial categories.

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Article Synopsis
  • Direct-acting antiviral (DAA) therapy for hepatitis C (HCV) is effective and well-received but remains out of reach for many due to cost issues.
  • A study followed women with HIV and HCV to analyze how health insurance status impacted their access to DAA treatment from 2015-2019.
  • Results showed that women with health insurance were significantly more likely to start DAA therapy compared to those without, suggesting that improving insurance coverage could enhance access to HCV treatment for those affected by HIV.
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