Publications by authors named "M H Adeline Yong"
Objective: To analyze the accuracy of ChatGPT-generated responses to common rhinologic patient questions.
Methods: Ten common questions from rhinology patients were compiled by a panel of 4 rhinology fellowship-trained surgeons based on clinical patient experience. This panel (Panel 1) developed consensus "expert" responses to each question.
Cytomegalovirus (CMV) infections continue to be associated with significant morbidity and mortality following solid organ transplantation and haemopoietic stem cell transplantation. Advances in understanding the biology of CMV in the immunosuppressed host will translate into improved management approaches and better clinical outcomes. Updated definitions of resistant and refractory CMV infections will lead to more consistent reporting of CMV outcomes, better inform appropriate antiviral strategies and influence clinical trial design.
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- The study aimed to investigate the potential of differentially expressed long non-coding RNAs (lncRNAs) in human peripheral blood mononuclear cells as biomarkers for postmenopausal osteoporosis (PMOP), comparing samples from PMOP patients and postmenopausal patients without osteoporosis.
- RNA sequencing revealed 1978 differentially expressed lncRNAs and 1024 mRNAs, with bioinformatics analysis showing these genes were primarily involved in pathways related to protein binding and key signaling pathways like PI3K-Akt.
- Further correlation analysis highlighted specific lncRNAs, such as RAB37, BEGAIN, and ZNF529, as potential diagnostic markers for PMOP based on their interaction with mRNAs
Background: Antimicrobial stewardship (AMS) guidelines now recommend antifungal stewardship (AFS) interventions to improve the management of invasive fungal diseases (IFDs). AFS programmes have not been reported in Australia.
Aims: To determine the monitoring of antifungal use, AFS strategies and targets, and barriers to AFS implementation in Australian hospitals.
Objective: More than 130 susceptibility loci for rheumatoid arthritis (RA) have been identified with genome-wide association studies (GWAS). To investigate the genetic predisposition of Chinese anti-cyclic-citrullinated-peptides-antibody-positive RA, we carried out an exome sequencing study.
Methods: Patients were recruited from three major public hospitals in Singapore, Tan Tock Seng Hospital (TTSH), Singapore General Hospital and National University Health System.