Clinical profile of patients with systemic lupus erythematosus.

Introduction: Clinical features of systemic lupus erythematosus vary between different parts of the World; however, this information on Nepalese systemic lupus erythematosus does not exist.

Methods: Patients with systemic lupus erythematosus fulfilling the American College of Rheumatology criteria treated in Patan Hospital were studied by means of retrospective review of their case records. The results were compared with various regional and international studies.

Eosinophilic fascitis: a rare fibrosing disorder.

Eosinophilic fasciitis is a rare systemic disease characterized by inflammatory thickening of the skin and underlying fascia, peripheral eosinophilia, elevated inflammatory markers and typical biopsy findings. Internal organ involvement is rare unlike in other fibrosing disorders. Though this is usually a benign disease, it is often difficult to diagnose and the course may also be variable.

Behçet's disease: an account of three cases.

Behçet's disease is a chronic relapsing inflammatory condition affecting multiple organ-systems of the body. Patient's with this disease present to different specialists with wide spectrum of clinical features of varying severity. Worldwide, this disease is clustered around certain parts of Asia, previously known as 'Silk route'.