Historical Drugs in Transylvania: Disclosing the Composition of Ointments from the "History of Pharmacy Collection" in Cluj-Napoca Through a Multi-Analytical Approach.

The National Museum of Transylvanian History in Cluj-Napoca, Romania, features a History of Pharmacy Collection that documents the evolution of pharmacies in the region since the 16th century. Within the "Pharmatrans" project (2021-2023), we investigated the chemical composition of ointments from fourteen historical pharmaceutical containers dating back to the 18th and 19th centuries. Most samples were from an aristocratic traveling medicine chest, a key artifact in the collection.

Ultraviolet-B Resonant-Cavity Light-Emitting Diodes with Tunnel Junctions and Dielectric Mirrors.

We demonstrate the first electrically injected AlGaN-based ultraviolet-B resonant-cavity light-emitting diode (RCLED). The devices feature dielectric SiO/HfO distributed Bragg reflectors enabled by tunnel junctions (TJs) for lateral current spreading. A highly doped n-AlGaN/n-GaN/p-AlGaN TJ and a top n-AlGaN current spreading layer are used as transparent contacts, resulting in a good current spreading up to an active region mesa diameter of 120 μm.

Hot Embossing to Fabricate Parylene-Based Microstructures and Its Impact on the Material Properties.

This study aims to establish and optimize a process for the fabrication of 3D microstructures of the biocompatible polymer Parylene C using hot embossing techniques. The different process parameters such as embossing temperature, embossing force, demolding temperature and speed, and the usage of a release agent were optimized, utilizing adhesive micropillars as a use case. To enhance compatibility with conventional semiconductor fabrication techniques, hot embossing of Parylene C was adapted from conventional stainless steel substrates to silicon chip platforms.

Skin optical properties from 200 to 300 nm support far UV-C skin-safety in vivo.

The growing threat of multi-drug resistant pathogens and airborne microbial diseases has highlighted the need to improve or develop novel disinfection methods for clinical environments. Conventional ultraviolet C (UV-C) lamps effectively inactivate microorganisms but are harmful to human skin and eyes upon exposure. The use of new 233 nm far UV-C LEDs as an antiseptic can overcome those limitations.