Publications by authors named "M Gurol"
Introduction: While cerebral amyloid angiopathy is likely responsible for intracerebral hemorrhage (ICH) occurring in superficial (grey matter, vermis) cerebellar locations, it is unclear whether hypertensive arteriopathy (HA), the other major cerebral small vessel disease (cSVD), is associated with cerebellar ICH (cICH) in deep (white matter, deep nuclei, cerebellar peduncle) regions. We tested the hypothesis that HA-associated neuroimaging markers are significantly associated with deep cICH compared to superficial cICH.
Patients And Methods: Brain MRI scans from consecutive non-traumatic cICH patients admitted to a referral center were analyzed for cSVD markers.
Article Synopsis
- - The study explores the link between acute hyperglycemia and intraventricular hemorrhage (IVH) following intracerebral hemorrhage (ICH), positing that IVH might lead to hyperglycemia due to a neuroendocrine stress response.
- - Analysis of data from the ICH Deferoxamine (i-DEF) trial and an independent cohort identified hyperglycemia, history of smoking, and non-lobar ICH location as significant predictors of IVH.
- - The findings suggest that hyperglycemia may reflect inflammatory responses to hemorrhage in the ventricles, indicating a need for further research into the underlying mechanisms.
Importance: Patients with atrial fibrillation (AF) can have an ischemic stroke (IS) despite oral anticoagulant (OAC) treatment. Knowledge regarding the association between OAC discontinuation and the subsequent risk of recurrent IS in patients with AF is limited.
Objectives: To determine the risk of recurrent IS in patients with AF receiving OAC and to evaluate the association between OAC discontinuation and the risk of recurrent IS.
Article Synopsis
- The study investigates the effectiveness of left atrial appendage closure (LAAC) in preventing recurrent strokes in patients with nonvalvular atrial fibrillation (NVAF) who experience acute ischemic strokes (AIS) despite being on oral anticoagulants (OAC).
- Over a follow-up period of approximately 1.75 years, the incidence of AIS after LAAC was significantly lower (1.97%) than the expected stroke risk based on patients' CHADS-VASc scores (8.44%), suggesting LAAC could be beneficial.
- These findings indicate a need for further randomized trials to explore the potential advantages of LAAC in this high-risk patient population, especially given that many patients discontinued OAC after