Topical Treatment of Elevated Intraocular Pressure in Patients with Graves' Orbitopathy.

: In this study, we evaluated the efficacy of topical hypotensive treatment and/or systemic corticosteroids therapy in patients with elevated intraocular pressure and Graves' orbitopathy (GO). : We included 172 eyes in 86 individuals with duration of GO ≥ 3 months, intraocular pressure in either eye ≥ 25.0 mmHg, and GO ranked ≥ 3 at least in one eye in modified CAS form.

Latanoprost is effective in reducing high intraocular pressure associated with Graves' ophthalmopathy.

Purpose: To assess the efficacy and tolerability of latanoprost in the treatment of glaucoma and ocular hypertension associated with Graves' ophthalmopathy. Prospective interventional case series.

Materials And Methods: 28 patients (19 females and 9 males) aged from 31 to 68 (mean age 45.

Pyruvate kinase activity in the placentas of women living in polluted and unpolluted environments.

Background: It was shown earlier that in women living in a polluted environment, the proportion of hypotrophic newborns was greater than in the general population. The placentas of these women show significant histological changes. The authors decided to check whether the activity of pyruvate kinase (PK), a key enzyme in the third stage of glycolysis, changes similarly.

Amino-acid composition of pyruvate kinase M2 isoenzyme variants from rat liver and Morris hepatoma 7777.

Cytosolic fractions B (salted out between 51-70% ammonium sulphate saturation) from rat liver and Morris hepatoma 7777, containing pyruvate kinase (EC 2.7.1.

Tumor-specific pyruvate kinase isoenzyme M2 involved in biochemical strategy of energy generation in neoplastic cells.

The differences in properties of pyruvate kinase (EC 2.1.7.