Publications by authors named "M Gule-Monroe"
Article Synopsis
- A retrospective study assessed the effectiveness of contrast-enhanced T1-weighted 3D SPACE MRI sequences versus 3D FLASH sequences in detecting brain metastases in patients at a single institution.
- The evaluation involved a review of cases where both imaging techniques were used, with assessments on factors like the number of lesions detected, image quality, and contrast-to-noise ratio (CNR) by certified neuroradiologists.
- Results showed that SPACE detected more metastatic lesions and had better image quality and fewer artifacts than FLASH, supporting SPACE as the superior method for brain metastasis detection.
Importance: Anaplastic thyroid carcinoma (ATC) is a rare and lethal cancer. Although progress has been made in recent years in patients with mutated BRAF tumors, those who respond initially eventually die of their disease; furthermore, there are no approved therapies for non-BRAF mutated tumors.
Objective: To determine whether treatment with matched-targeted therapy plus immune checkpoint inhibitors were associated with improved overall survival (OS).
Advanced MRI-based neuroimaging techniques, such as perfusion and spectroscopy, have been increasingly incorporated into routine follow-up protocols in patients treated for high-grade glioma (HGG), to help differentiate tumor progression from treatment effect. However, these techniques' influence on clinical management remains poorly understood. The purpose of this article was to evaluate the impact of MRI-based advanced neuroimaging on clinical decision-making in patients with HGG after treatment.
View Article and Find Full Text PDFThe dabrafenib plus trametinib combination (DT) has revolutionized the treatment of -mutated anaplastic thyroid carcinoma (BRAFm-ATC). However, patients eventually develop resistance and progress. Single-agent anti-PD-1 inhibitor spartalizumab has shown a median overall survival (mOS) of 5.
View Article and Find Full Text PDFTinnitus is abnormal perception of sound and has many subtypes. Clinical evaluation, audiometry, and otoscopy should be performed before ordering any imaging, as the choice of imaging will depend on various factors. Type of tinnitus (pulsatile or nonpulsatile) and otoscopy findings of a vascular retrotympanic lesion are key determinants to guide the choice of imaging studies.
View Article and Find Full Text PDF