Data Resource Profile: The Cancer Public Library Database in South Korea.

This paper provides a comprehensive overview of the Cancer Public Library Database (CPLD), established under the Korean Clinical Data Utilization for Research Excellence project (K-CURE). The CPLD links data from four major population-based public sources: the Korea National Cancer Incidence Database in the Korea Central Cancer Registry, cause-of-death data in Statistics Korea, the National Health Information Database in the National Health Insurance Service, and the National Health Insurance Research Database in the Health Insurance Review & Assessment Service. These databases are linked using an encrypted resident registration number.

Acromegaly: Clinical Care in Central and Eastern Europe, Israel, and Kazakhstan.

Acromegaly is a rare condition typically caused by benign pituitary adenomas, resulting in excessive production of growth hormone. Clinical manifestations of acromegaly are diverse, varying from the overgrowth of body tissue to cardiovascular, metabolic, and osteoarticular disorders. Symptoms may emerge slowly, overlapping with other diseases and often involve many different healthcare specialists.

[Blood flow changes in the brain, kidneys and caudal vena cava as affected by diprazin].

It has been shown by hydrogen clearance that diprazine (1 mg/kg) given to anesthetized cats reduces the total brain blood flow and local circulation in the cortex of the frontal lobe in the presence of a decrease in arterial pressure and blood flow in the kidneys and caudal vena cava. In intact rabbits, there is an increase in the total and local circulation in the frontal and temporal lobes of the brain followed by a decrease. Diprazine-induced changes in the brain blood flow are phasic in nature and characterized by labile redistribution of the blood flow between the different brain lobes.