Does a Specific Sequential Combination of Antiseptic Solutions for Chemical Debridement in Periprosthetic Joint Infection Improve Outcomes vs. Solution Alone? An In Vivo Study.

: Chemical debridement is a fundamental step during the surgical treatment of both acute and chronic periprosthetic joint infection (PJI). However, there is no consensus on the optimal solution, nor is there sufficient evidence on the optimal irrigation time and combination of solutions. In an in vitro study, our group recently demonstrated that sequential combination debridement (SCD) with 3% acetic acid (AA) followed by 10% povidone iodine (PI) and 5 mM hydrogen peroxide (HO) was the best strategy for reducing bacterial load.

Tc-DTPA-Collagen Radiotracer for the Noninvasive Detection of Infective Endocarditis.

Infective endocarditis (IE) represents a significant concern among hospital-acquired infections, frequently caused by the Gram-positive bacterium . Nuclear imaging is emerging as a noninvasive and precise diagnostic tool. However, the gold standard radiotracer [F]-FDG cannot distinguish between infection and inflammation, resulting in false positives.

Optimizing phosphorus precipitation from acidic sewage sludge ash leachate: Use of Mg-rich mining by-products for enhanced nutrient recovery.

Phosphorus recovery from Sewage Sludge Ashes (SSA) by wet chemical extraction followed by selective precipitation has gained great attention in recent years, attempting to reduce the anthropic pressure on natural reserves. This study investigates the selective precipitation process at lab- and small pilot-scales by means of two conventional and one innovative precipitating agents, the latter derived from a low-grade magnesium oxide mining by-product (LG-MgO named PC8), assessing the role of the most relevant operating parameters. Lab-scale experiments were performed on leachates obtained from bottom and fly ashes, in which several operating conditions were tested, differing in the type of precipitating agent, target pH and nutrient molar ratio.