Publications by authors named "M Grzesiak"
Generation of reactive oxygen species (ROS) within the ER evokes stress leading to immunogenic cell death. A red light activated BODIPY dye capable of subcellular localization within the ER producing high quantum yields of ROS is reported. The ability of this dye to act as a photodynamic therapy (PDT) agent in breast cancer cells suggests promising organelle-targeted therapeutics.
View Article and Find Full Text PDFThe aim of this research was to determine the effect of strawberry seed oil addition to rabbit feed on slaughter performance traits, meat quality traits and plasma cholesterol and triglycerides of purebred Termond White rabbits ( = 24). The experiment used young rabbits born to 6 does. From each litter, two rabbits were randomly assigned into one of the two groups.
View Article and Find Full Text PDFIn this work, we aimed to determine the role of activin A during crucial events of mouse embryogenesis and distinguish the function of the protein of zygotic origin and the one secreted by the maternal reproductive tract. To this end, we recorded the progression of development and phenotype of Inhba knockout embryos and compared them with the heterozygotes and wild-type embryos using time-lapse imaging and detection of lineage-specific markers. We revealed that the zygotic activin A deficiency does not impair the course and rate of development of embryos to the blastocyst stage.
View Article and Find Full Text PDFBackground: Subsequent randomized controlled trials (RCTs) comparing the clinical outcomes of fractional flow reserve (FFR)-guided and angiography-guided revascularisation in patients with coronary artery disease (CAD) yielded inconsistent results.
Aims: This study aimed to assess head to head whether FFR-guided revascularisation reduces the rates of hard clinical endpoints in comparison with the angiography-guided approach alone.
Methods: This systematic review was conducted through June 2024 at Embase, Clinicaltrials.