Publications by authors named "M Grosshans"

The objective of this systematic review was to characterize the literature regarding the risk factors associated with the development of toxic shock syndrome (TSS) secondary to the use of intrauterine contraceptives (IUCs), as well as patient outcomes. A literature search was conducted spanning origin through December 12, 2022, using Embase and MEDLINE ALL. Primary literature that discussed development of TSS along with the presence of an IUC were included.

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Artificial intelligence (AI) offers a wealth of opportunities for medicine, if we also bear in mind the risks associated with this technology. In recent years the potential future integration of AI with medicine has been the subject of much debate, although practical clinical experience of relevant cases is still largely absent. This case study examines a particular patient's experience with different forms of care.

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Article Synopsis
  • Pregabalin, originally approved for conditions like neuropathic pain and anxiety, has seen a significant rise in abuse, especially noted in Swiss prisons and forensic hospitals.
  • A study surveying 131 physicians revealed that 82.5% observed increasing pregabalin use, with 89.1% of patients requesting it without proper medical justification, often in combination with other drugs.
  • Many physicians reported patients taking dangerously high doses (up to 4,200 mg/day) and experiencing withdrawal symptoms, predominantly affecting foreign patients from Northwest Africa, leading to a consensus to reduce or discontinue prescriptions in problematic cases.
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Prevalence rates of overweight and obesity are increasing worldwide and are amongst the leading causes of death. Participants with obesity also suffer from poorer mental health with a concomitant reduced quality of life. Bariatric surgery outperforms other existing weight optimization approaches.

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There is increasing evidence that brain-derived neurotrophic factor (BDNF) impacts on the development of obesity. We are the first to test the hypothesis that BDNF levels might be associated with neural reactivity to food cues in patients suffering from obesity and healthy controls. We assessed visual food cue-induced neural response in 19 obese patients and 20 matched controls using functional magnetic resonance imaging and analyzed the associations between BDNF levels, food cue-reactivity and food craving.

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