Publications by authors named "M Groschl"

Article Synopsis
  • - The study investigates the development of the early-morning peak in cortisol levels in infants, which is crucial for determining effective hydrocortisone therapy for adrenal insufficiency.
  • - Researchers conducted a systematic review and meta-analysis, analyzing data from 54 publications and 1,904 infants to study how salivary cortisol varies with age and time of day.
  • - Findings reveal that the morning/evening cortisol ratio increases significantly as infants grow, establishing a consistent 24-hour rhythm by 6-9 months.
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Multilayer piezoelectric transducers and resonators are widely used for generating propagating and standing acoustic waves as well as for sensor devices. More recently, layered piezoelectric structures based on thin film technology became increasingly important for electromechanical filters used in mobile phones. As a consequence, analytical mathematical modeling of such structures is of high interest.

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We trained a deep learning algorithm to use skin optical coherence tomography (OCT) angiograms to differentiate between healthy and type 2 diabetic mice. OCT angiograms were acquired with a custom-built OCT system based on an akinetic swept laser at 1322 nm with a lateral resolution of ∼13 μm and using split-spectrum amplitude decorrelation. Our data set consisted of 24 stitched angiograms of the full ear, with a size of approximately 8.

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Background: Cognitive impairment associated with schizophrenia predicts poor functional outcomes, but currently no approved pharmacotherapy is available. This study investigated whether the glycine transporter-1 inhibitor BI 425809 improves cognition in patients with schizophrenia.

Methods: This phase 2, randomised, double-blind, placebo-controlled, parallel-group trial (81 centres, 11 countries), randomly assigned outpatients (aged 18-50 years) with schizophrenia on stable treatment to add-on once-daily oral BI 425809 2 mg, 5 mg, 10 mg, or 25 mg or placebo (1:1:1:1:2) for 12 weeks.

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