Ultrasmooth Micromilling of Stainless Steel by Ultrashort Pulsed Laser Ablation Using MHz Bursts.

Ultrashort pulsed (USP) laser burst ablation has attracted numerous interests for its great potential in enhancing ablation efficiency and reducing the heat-affected zone. However, little attention has been paid to the influence of burst ablation on the processed surface quality. To fill this research gap, the present study conducts a comprehensive investigation on the surface processing of stainless steel using ultrashort pulsed laser burst ablation.

Development of the Dutch translational knowledge agenda for inherited metabolic diseases.

Background: Inherited metabolic diseases (IMDs) may have considerable implications for patients and their families. Despite their individual rarity, covering a spectrum of over 1800 distinct diseases, the diseases collectively exert a significant impact, with often lifelong disabilities. The United for Metabolic Diseases consortium was established to catalyze research with translation into the best possible care.

Pneumomediastinum complicating diabetic ketoacidosis.

Pneumomediastinum is an uncommon finding in patients with diabetic ketoacidosis (DKA) and may occur spontaneously or secondary to an effort rupture of the oesophagus. Excluding oesophageal rupture is important, as delaying treatment increases the risk of mortality. We discuss a case of DKA complicated by vomiting, pneumomediastinum, pneumopericardium and air in the epidural space.

Laser texturing of a St. Jude Medical RegentTM mechanical heart valve prosthesis: the proof of concept.

Objectives: The liquid-solid interactions have attracted broad interest since solid surfaces can either repel or attract fluids, configuring a wide spectrum of wetting states (from superhydrophilicity to superhydrophobicity). Since the blood-artificial surface interaction of bileaflet mechanical heart valves essentially represents a liquid-solid interaction, we analysed the thrombogenicity of mechanical heart valve prostheses from innovative perspectives. The aim of the present study was to modify the surface wettability of standard St.

Reducing complexity: explaining inborn errors of metabolism and their treatment to children and adolescents.

Background: Inborn errors of metabolism (IEM) are a group of rare, heterogeneous and complex genetic conditions. Clinically, IEM often affect the central nervous system and other organs. Some carry the risk of progression and / or potentially life-threatening crises.