Publications by authors named "M Grehn"
Background/purpose: High doses to healthy cardiac substructures (CS) in stereotactic arrhythmia radioablation (STAR) raise concerns regarding potential treatment-induced cardio-toxicity. However, CS contours are not routinely created, hindering the understanding of the CS dose-effect relationships. To address this issue, the alignment of CS contouring was initiated within the STOPSTORM consortium.
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- - The study focuses on Stereotactic Arrhythmia Radioablation (STAR) as a treatment for ventricular tachycardia (VT), especially when traditional catheter-based methods are not viable, emphasizing the challenges in accurately defining treatment targets based on electro-anatomic maps (EAM).
- - Two different software solutions were evaluated for their effectiveness in transferring 2D target data from EAM into 3D CT volume coordinates, with a cross-validation study conducted on data from ten patients.
- - Results showed that the target volumes and surface areas obtained from both methods were nearly identical, suggesting that both software solutions are reliable for ensuring quality assurance and enhancing treatment accuracy in STAR procedures.
Purpose: STereotactic Arrhythmia Radioablation (STAR) showed promising results in patients with refractory ventricular tachycardia. However, clinical data are scarce and heterogeneous. The STOPSTORM.
View Article and Find Full Text PDFStereotactic arrhythmia radioablation (STAR) is a noninvasive treatment of refractory ventricular tachycardia (VT). In this study, we aimed to systematically review prospective trials on STAR and pool harmonized outcome measures in a meta-analysis. After registration in the International Prospective Register of Systematic Reviews (PROSPERO: CRD42023439666), we searched OVID Medline, OVID Embase, Web of Science Core Collection, the Cochrane Central Register of Controlled Trials, and Google Scholar on November 9, 2023, to identify reports describing results of prospective trials evaluating STAR for VT.
View Article and Find Full Text PDFBackground And Purpose: In patients with recurrent ventricular tachycardia (VT), STereotactic Arrhythmia Radioablation (STAR) shows promising results. The STOPSTORM.eu consortium was established to investigate and harmonise STAR treatment in Europe.
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