Publications by authors named "M Greensmith"
Background: Surgical resection, where appropriate, remains one of the best treatment options for hepatocellular carcinoma (HCC), however outcomes can be compromised by the development of liver failure. We reviewed our experience of liver resection for HCC patients to identify factors that may predict the development of post-hepatectomy liver failure (PHLF) and survival.
Methods: A single centre retrospective cohort study.
Aim: A large, prospectively collected, clinical database was analysed to determine the various pre- and intra-operative factors affecting anastomotic leakage (AL) in colorectal surgery.
Method: Data on 17 518 patients having a colorectal resection with anastomosis, taken from the 2013 American College of Surgeons National Surgical Quality Improvement Program database, were included in the study. Multivariable logistic regression analysis was carried out to identify risk-adjusted predictive factors for AL.
Introduction: There have been substantial changes in the provision of surgical services and in surgical training over the last twenty years. Consultants now have a much greater role in delivery of care, but concerns have been raised over surgical trainees' lack of experience, particularly with trauma and emergency cases.
Methods: The logbooks of surgical trainees undertaking 6 month posts during 1992-3 and 2009-12 in both the United Kingdom (UK) and South Africa (RSA) were analysed.
Background: Lamivudine therapy is effective for chronic hepatitis B infection in adults. We evaluated the efficacy and tolerability of lamivudine as a treatment for chronic infection with hepatitis B virus (HBV) in children.
Methods: Children with chronic hepatitis B were randomly assigned in a 2:1 ratio to receive either oral lamivudine (3 mg per kilogram of body weight; maximum, 100 mg) or placebo once daily for 52 weeks.