Publications by authors named "M Grandin"

Article Synopsis
  • The study aimed to identify factors that lead to both general and inappropriate antibiotic prescriptions for residents with lower respiratory tract infections (LRTI) in long-term care facilities (LTCFs).
  • Conducted in Western Switzerland, researchers observed 114 residents and found that over half received antibiotics, but a significant portion of these prescriptions were deemed inappropriate.
  • The use of diagnostic tests, particularly PCR for respiratory viruses, was linked to reduced antibiotic prescriptions, suggesting that enhanced testing could improve prescribing practices in LTCFs.
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Solar wind-magnetosphere coupling drives magnetospheric dynamic phenomena by enabling energy exchange between magnetospheric and solar wind plasmas. In this study, we examine two-dimensional noon-midnight meridional plane simulation runs of the global hybrid-Vlasov code Vlasiator with southward interplanetary magnetic field driving. We compute the energy flux, which consists of the Poynting flux and hydrodynamic energy flux components, through the Earth's magnetopause during flux transfer events (FTEs).

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Geospace plasma simulations have progressed toward more realistic descriptions of the solar wind-magnetosphere interaction from magnetohydrodynamic to hybrid ion-kinetic, such as the state-of-the-art Vlasiator model. Despite computational advances, electron scales have been out of reach in a global setting. eVlasiator, a novel Vlasiator submodule, shows for the first time how electromagnetic fields driven by global hybrid-ion kinetics influence electrons, resulting in kinetic signatures.

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Shock waves in collisionless plasmas are among the most efficient particle accelerators in space. Shock reformation is a process important to plasma heating and acceleration, but direct observations of reformation at quasi-parallel shocks have been lacking. Here, we investigate Earth's quasi-parallel bow shock with observations by the four Magnetospheric Multiscale spacecraft.

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Geno- and phenotypic heterogeneity amongst cancer cell subpopulations are established drivers of treatment resistance and tumour recurrence. However, due to the technical difficulty associated with studying such intra-tumoural heterogeneity, this phenomenon is seldom interrogated in conventional cell culture models. Here, we employ a fluorescent lineage technique termed "optical barcoding" (OBC) to perform simultaneous longitudinal tracking of spatio-temporal fate in 64 patient-derived colorectal cancer subclones.

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