Left ventricular chamber dimensions and wall thickness by cardiovascular magnetic resonance: comparison with transthoracic echocardiography.

Aims: Cardiovascular magnetic resonance (CMR) is a reference standard imaging technique in assessment of cardiomyopathies due to the accurate measurement of cardiac volumes and mass. In clinical routine, transthoracic echocardiography (TTE) is the standard first-line technique and is commonly used for follow-up. In this study we examined how CMR-derived measurement of left ventricular (LV) chamber dimensions and wall thickness correspond to TTE.

New diagnostics with wireless pressure monitoring.

Hypertonia and heart failures have become two of the main diseases affecting today's human population. A telemetric controlled sensor implant without a battery is being developed and evaluated with in vivo experiments for use as a powerful tool in long-term post surgical evaluation of heart pressure, body temperature and pulse rate. Its capabilities are reported here.

Effects of abciximab and tirofiban on vitronectin receptors in human endothelial and smooth muscle cells.

human umbilical venous endothelial cells. 7E3 binding correlated with alphavbeta3-expression in all cell types. Integrin-mediated cell functions were analysed with adhesion and spreading assays on vitronectin.

Phosphorylation of phosphofructokinase by protein kinase C changes the allosteric properties of the enzyme.

The Ca2+- and phospholipid-dependent protein kinase C from rat brain phosphorylates rabbit muscle phosphofructokinase at the same trypsin-labile site as cyclic AMP-dependent protein kinase. However, protein kinase C also effectively phosphorylates one or more separate sites. Incubation of phosphofructokinase in the presence of protein kinase C, phospholipids, Ca2+, and ATP appears to affect the allosteric properties of phosphofructokinase by shifting the fructose 6-phosphate saturation curve to lower substrate concentrations in a time-dependent manner and decreasing cooperativity of the enzyme.