Publications by authors named "M Gornet"
This study investigates the use of magnetic resonance spectroscopy (MRS) to identify the intervertebral disc (IVD) as a pain generator, explore the pathophysiology of the biochemical and structural components of discogenic low back pain (DLBP), and present potential evidence of physiological responses to spinal manipulation therapy (SMT). A 29-year-old male presented with uncomplicated low back pain (LBP). The non-specific presentation and clinical examination findings were consistent with an initial working diagnosis of non-specific LBP with the clinician suspecting IVD as a likely pain generator.
View Article and Find Full Text PDFBackground: Progenitor cells derived from intervertebral disc tissue demonstrated immunomodulatory and regenerative properties in preclinical studies. We report the safety and efficacy results of a US Food and Drug Administration-approved clinical trial of these cells for the treatment of symptomatic degenerative disc disease.
Methods: Sixty patients with symptomatic single-level lumbar degenerative disc disease (mean age 37.
Given the unremitting obstacles to effectively screen for and treat ovarian cancer (OC), prevention is a necessary countermeasure. The recent discovery of the fallopian tube as the origin of the most common and deadly type of OC, high grade serous cancer (HGSC), makes prevention through salpingectomy possible (Madsen et al., 2015).
View Article and Find Full Text PDFArticle Synopsis
- This text reports the first case of robotic-assisted utero-ovarian transposition performed on a 36-year-old woman with uterine fibroids who needed fertility preservation due to rectal cancer treatment involving pelvic radiation.
- The procedure involved moving the uterus and ovaries to the upper abdomen to protect them during chemotherapy and radiation, allowing the patient to maintain her fertility options.
- The woman's surgery was successful, and she completed her cancer treatment with a complete response, opting for ongoing surveillance afterward.
Article Synopsis
- The study aims to validate the use of magnetic resonance spectroscopy (MRS) as a reliable diagnostic tool for identifying painful lumbar discs, comparing it with the existing gold standard, low-pressure provocative discography (PD).
- Results indicate that MRS-derived measures, specifically NOCISCORE and SI-SCORE, demonstrate high accuracy and reliability in differentiating between painful and non-painful discs, achieving 100% sensitivity and specificity.
- The findings suggest that MRS can effectively predict disc pain and degeneration, providing a non-invasive alternative with potential clinical benefits for patient management.