Genistein supplementation has no effects on vitamin D levels in healthy Spanish postmenopausal women.

In vitro studies have shown that genistein inhibits the CYP240 enzyme, which is involved in the degradation of 1,25-dihydroxycholecalciferol and its precursor 25-hydroxycholecalciferol, and increases their plasma levels. However, no clinical studies have primarily assessed the synergistic effect of isoflavones on vitamin D levels. The aim of this study was to evaluate the possible additive effect of genistein supplementation on vitamin D levels, calcium metabolism and bone remodeling markers in healthy postmenopausal women during the spring-summer months.

Influence of the diagnostic protocol and age on the prostate cancer incidence rate in Castilla y León according to the national registry 2010.

Objective: Cross-sectional descriptive observational study of incidence and association, to determine whether the higher incidence of prostate cancer in Castilla y León (with respect to the national rate) could be due to modifiable factors.

Location: University Hospital Río Hortega.

Participants: New prostate cancer diagnoses.

Acute calculous cholecystitis: a real-life management study in a tertiary teaching hospital.

Aim: to describe the management of acute calculous cholecystitis in a tertiary teaching hospital and the outcomes obtained.

Material And Methods: a retrospective single tertiary center cohort study.

Results: medical records of 487 patients were analyzed.

Comparative study of the prevalence of the human papilloma virus in Spanish and foreign women participating in a population screening programme in Castilla y León.

Introduction: The objective of this study was to compare the prevalence of human papilloma virus (HPV) in Spanish and foreign women in a cervical cancer screening programme of Castilla y León and foreign women living in the community who participated in the programme.

Methods: This was an observational, descriptive, cross - sectional, retrospective study of period prevalence. The sample consisted of all the women included in the cervical cancer prevention programme of the Regional Ministry of Health of the Junta de Castilla y León who were screened for cervical cancer during the period from 2012 to 2014, aged between 25 and 64 years of age.

[Episodes of nontyphoidal salmonellosis in adult patients of the Valladolid West Area in 2017: Evaluation of the suitability of the microbiological culture request and the prescribed treatment].

Objective: Gastroenteritic salmonellosis is still the second cause diagnosed of infectious diarrhea, most of these clinical pictures are mild and self-limited and therefore the use of antibiotics is limited to few cases. The aim of the study was to describe the episodes of diarrhea caused by Salmonella enterica subsp. enterica, assessing the suitability of the request and the use of antibiotics according to the criteria included in the methodology.