Publications by authors named "M Gonzalez-Gay"
IgA vasculitis (IgAV), previously named as Henoch-Schönlein purpura, is the most frequent systemic vasculitis in children. In adults, IgAV is less common although it is associated with more severe disease. In fact, the frequency of glomerulonephritis (referred to as IgAV nephritis) in adults is higher than in children and tends to present more severely, with around 10-30% of those affected eventually progressing to end-stage renal disease.
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- Polymyalgia Rheumatica (PMR) is an inflammatory condition commonly affecting people over 50, with glucocorticoids being the main treatment despite their side effects and risk of relapses upon tapering.
- This review explores traditional PMR management and highlights emerging therapies, especially glucocorticoid-sparing agents like methotrexate and biologic agents, which show promise in reducing glucocorticoid use and managing the disease effectively.
- The effectiveness of biologics, particularly anti-IL-6 receptor agents such as tocilizumab and sarilumab, has been noted for their ability to decrease relapse rates and help achieve long-term remission in PMR patients.
: Inflammatory bowel disease (IBD) is associated with an increased prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD). The Fibrosis-4 (FIB-4) index is a non-invasive tool for assessing liver fibrosis that has been validated in various liver diseases. The main objective of this study was to study whether the FIB-4 index is a reliable predictor of liver fibrosis, as assessed through elastography, in patients with IBD.
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