FRENCH MARIGOLD (TAGETES PATULA L.) FLOWER EXTRACT PROTECTS KIDNEY CELLS FROM INFLAMMATION IN VITRO.

The aim of our study is to evaluate the mechanisms of anti-inflammatory property of Tagetes patula L. (French Marigold) flower extracts and its protective effect on renal epithelium against uropathogenic E. coli infection.

Total polyphenols and antioxidant activity in different species of apples grown in Georgia.

Many studies have shown that biologically active components in plant-based foods, particularly phytochemicals, have important potential to modulate many processes in the development of diseases, including cancer, cardiovascular disease, diabetes, pulmonary disorders, Alzheimer's disease, and other degenerative diseases. The aim of the our study was to provide an updated understanding and analysis of various apple sorts growing in Georgia by the compounds with a particular focus on their potential role(s) in disease risk and general human health. The Various sorts (Kekhura, Banany, Golden, Starty, Chempion, Aidaridy, Brotsky, Achabety, Sinapy, Jonagold and Antonovka,) of apples were investigated.

[Treatment of nonalcogolic fatty disease of liver].

The experimental and clinical data concerning of treatment of nonalcogolic fatty liver disease (NAFLD) are summarized and analyzed in the review. Some aspects of pathogenetic pharmacotherapy of NAFLD have been discussed (correction of insulin resistance, obesity, dislipidemia, oxidative stress, hepatoprotectors, restoration of intestine microbiosis, replacement hormonal, syndrome and antihypertensive drugs). Medical and non - medical methods of treatment is compared.

[Peculiarities of metabolic syndrome and nonalcogolic fatty liver disease in menopausal women].

Correlation between menopause metabolic syndrome and nonalcogolic fatty liver disease (NAFLD) is reviewed. NAFLD refers to a wide spectrum of liver disease ranging from simple fatty liver (steatosis), to nonalcoholic steatohepatitis, to cirrhosis. The causes and pathogenetic factors of the disease are still under investigation.

[Changes of metabolic indices caused by berberin and extract, obtained from the bark of Phellodendron lavalei, introduced in subtropic regions of Georgia, in streptozotocin induced diabetic rats].

The goal of the study was to identify changes in lipid metabolism, functional condition of liver and kidney influenced by berberin and extract, obtained from the bark of Рhеllodendron lavalei, introduced in sub tropic regions of Georgia, in streptozotocin induced diabetic rats. Diabetes in animals was induced by single intraperitoneal injection of streptozotocin in 1 M citrate buffer, pH 4.5, dose 40 mg/kg per body weight, 1 ml volume.