Publications by authors named "M Gomez-Bueno"

Background: There is a long-standing need for a noninvasive biomarker that allows monitoring of cardiac allograft rejection, avoiding the need for periodic endomyocardial biopsies (EMB).

Methods: Multicenter, observational, prospective study, performed between 2019 and 2023 (NCT04973943). All patients underwent 7 per-protocol surveillance EMB during the first postheart transplantation year.

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  • The study investigates the incidence, mechanisms, and predictors of sudden death (SD) in patients with cardiac amyloidosis, a serious heart condition.
  • It analyzed data from 784 patients with either ATTR or AL cardiac amyloidosis, finding that SD is more common in AL patients compared to those with ATTR.
  • Key risk factors for SD include previous pacemaker implantation for ATTR patients and the use of beta-blockers and advanced heart failure symptoms (NYHA III-IV) for AL patients.
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  • * A total of 245 patients were analyzed, with 54.3% using mechanical LV unloading techniques, primarily the intra-aortic balloon pump, showing an improved 1-year survival rate of 74.4% compared to 59.8% in those without LV unloading.
  • * The findings suggest that preoperative LV unloading is linked to better survival rates after a year post-transplant, with no notable differences in other postoperative complications between groups.
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Background: The current incidence and outcomes of structural transcatheter procedures in heart transplant (HTx) recipients and left-ventricular assist devices (LVAD) carriers is unknown.

Aims: To provide insights on structural transcatheter procedures performed across HTx and LVAD patients in Spain.

Methods: Multicenter, ambispective, observational nationwide registry.

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