Venous thromboembolism risk in amyotrophic lateral sclerosis: a hospital record-linkage study.

Background: Venous thromboembolism (VTE) can occur in amyotrophic lateral sclerosis (ALS) and pulmonary embolism causes death in a minority of cases. The benefits of preventing VTE must be weighed against the risks. An accurate estimate of the incidence of VTE in ALS is crucial to assessing this balance.

Risk of self-harm in patients with eating disorders: English population-based national record-linkage study, 1999-2021.

Objective: Anorexia nervosa (AN) and bulimia nervosa (BN) are eating disorders associated with high rates of self-harm (SH). This is the first national study in England to quantify this association in a hospital population.

Method: A retrospective cohort study using a linked national dataset of Hospital Episode Statistics for 1999-2021.

Low risk of some common cancers in women with anorexia nervosa: Evidence from a national record-linkage study.

Background: Some studies report that women with anorexia nervosa (AN) have lower risk than others of breast cancer, but increased risk of cancers of other sites. No work has been done to quantify the risk in the English population.

Methods: Retrospective cohort study using a national linked dataset of Hospital Episode Statistics for 1999-2021.

Central nervous system abscesses and empyemas in England: epidemiological trends over five decades.

Objectives: To report on population-based epidemiological trends in central nervous system (CNS) abscesses and empyemas in England over five decades.

Methods: Trend analyses of age-sex-specific hospital admission and death rates using routinely collected English national hospital discharge records, mortality records, and annual population denominators from 1968 to 2019.

Results: Hospital admission rates for CNS abscesses and empyemas were stable in England until the late 1980s.