Treatment of Symptomatic Focal Hepatic Hemangioma with Propranolol in Neonates: Is It Efficient?

Hepatic hemangiomas (HH) - classified into congenital hepatic hemangiomas (CHH) or infantile hepatic hemangiomas (IHH) - are benign vascular tumors that are mainly asymptomatic, but may cause clinical problems that require treatment. While focal, multifocal, and diffuse IHH are responsive to propranolol treatment, CHH is mainly focal and thought to be resistant to treatment with propranolol. The clinical and imaging distinctions between CHH and IHH in cases of focal lesions can be challenging, while histopathological distinction is mostly lacking in the clinical setting.

Contrast-enhanced ultrasound in detection and follow-up of focal renal infections in children.

Objective: Focal renal infections in children have to be diagnosed early in order to enable an appropriate antibiotic treatment. The purpose of this paper was to investigate the efficacy and clinical utility of intravenous renal contrast-enhanced ultrasound (CEUS) as an alternative imaging method for the diagnosis and follow-up of focal renal infections in children.

Methods: Fourteen children aged from 6 months to 17 years (mean 6.

Potential causes of insufficient bladder contrast opacification and premature microbubble destruction during contrast-enhanced voiding urosonography in children.

Contrast-enhanced voiding urosonography (ceVUS) has been recognized as a child-friendly examination with high diagnostic accuracy for vesicoureteric reflux detection. A single bolus and the infusion techniques of ceVUS are described. Insufficient bladder contrast opacification during the filling phase and premature destruction of SonoVue microbubbles might occur.

The binding sites of cadmium to a reduced form of glutathione.

Glutathione is the most abundant low molecular weight thiol-containing molecule in biological cells with a strong tendency to interact with metal ions. Among the eight possible glutathione binding sites, only two are determined as groups that interact with the Cd2+ ion. Analysis of vibrational spectra and 13C and 1H NMR spectra revealed that thiol and glutamyl's carboxylic groups are groups that cooperate in interaction with Cd2+ ions.