Publications by authors named "M Giovinazzo"

In partnership with clinician advisors, a text-based program, BeWell, was co-created to support clinician well-being at a Canadian mental health hospital. This paper briefly describes the process of designing BeWell with clinician advisors and highlights key lessons learned in engaging clinicians as advisors in the design and development of a digital health intervention. The lessons learned can serve as best practices for health systems, organizations, and researchers to consider when engaging clinicians in the design, development, and implementation of digital health interventions.

View Article and Find Full Text PDF

Exercise-induced increases in pulmonary blood flow normally increase pulmonary arterial pressure only minimally, largely due to a reserve of pulmonary capillaries that are available for recruitment to carry the flow. In pulmonary arterial hypertension, due to precapillary arteriolar obstruction, such recruitment is greatly reduced. In exercising pulmonary arterial hypertension patients, pulmonary arterial pressure remains high and may even increase further.

View Article and Find Full Text PDF

Pulmonary arterial pressure rises minimally during exercise. The pulmonary microcirculation accommodates increasing blood flow recruitment of pulmonary capillaries and, at higher flows, by distention of already perfused capillaries. The flow transition range between recruitment and distention has not been studied or compared across mammalian species, including humans.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates how cardiac output (CO) and pulmonary artery pressure (PAP) respond to exercise in humans, highlighting the mechanisms of capillary recruitment and distention during increased blood flow.
  • It involved ten subjects undergoing exercise testing, with measurements showing significant increases in CO and PAP, while a decrease in the metabolism of a specific compound (BPAP) was observed at peak exercise.
  • The results indicate that during moderate exercise, capillary recruitment is the primary response to increasing blood flow, whereas in one subject with already high CO, further increases were linked to capillary distention, providing insights into exercise physiology and pulmonary hypertension.
View Article and Find Full Text PDF

Placentophagia (consuming the placenta) has historically not been a common practice among humans. Over the past few decades the practice has gained attention as more women, particularly educated, middle-class, White American women, choose to partake in this practice. Purported benefits of placentophagia include pain relief, increased breast milk production, and decreased risk of postpartum depression; however, there is a lack of evidence to support these claims.

View Article and Find Full Text PDF