Standardization of Bone Marrow Reporting for Myelodysplastic Syndromes/Neoplasms on Behalf of the International Consortium for Myelodysplastic Syndromes/Neoplasms.

Context.—: Standardized bone marrow reporting specifically for myelodysplastic syndromes/neoplasms (MDS) is currently lacking in the literature and much needed in practice.

Objective.

How do the motor efficiency and visuo-spatial skills of primary school children relate to their teachers' evaluation of visuo-spatial skills?

This study mainly intended to examine whether the objective motor and visuospatial measures assessed in school-aged children predicted the evaluations expressed by their teachers. Moreover, it was investigated whether the pupils identified by their teachers as those with the poorest visuospatial skills also exhibited the worst performance in an instrumentally administered functional mobility task using wearable inertial sensors. Non-verbal fluid reasoning, visuospatial fluency, spatial understanding, and mobility (i.

Relative age effects in European soccer: their association with contextual factors, impact on youth national teams' performance, and presence at the senior level.

Introduction: Soccer systems promote early identification and specialisation practices to satisfy short- and long-term goals-both from sporting performance and financial gains perspectives. In this context, players are (de)selected based on observed performance level and on their ability to conform to given organisational demands, leading to the proliferation of selection biases, such as relative age effects (RAEs), which research has shown to influence both developmental experiences and senior career achievements. Accordingly, this study aims to: (a) investigate the magnitude of RAEs among youth national teams competing in the UEFA U17 European Soccer Championship, and their associations with teams' final ranking, (b) examine whether RAEs magnitude could be linked to cultural and contextual factors, and (c) further explore RAEs at senior level.

Safety Run-In and Part 1 of GIMEMA AML1718: Venetoclax Combined with FLAI as Induction Treatment in Non-Low-Risk AML.

The standard induction treatment for acute myeloid leukemia (AML) has limited efficacy for patients with non-low-risk AML. We conducted a multicenter study phase 1b/2, GIMEMA AML1718, to investigate the safety and efficacy of venetoclax (VEN) combined with fludarabine, cytarabine, and idarubicin (V-FLAI) as an induction therapy for non-low-risk AML patients younger than 65 years and at intermediate or high ELN risk. After a safety run-in, patients were randomly allocated to VEN 400 mg or VEN 600 mg cohorts.

Use of wearable sensors for continuous field monitoring of upper arm and trunk postures among construction workers.

Construction is considered amongst the highest risk sectors for the development of work-related musculoskeletal disorders (MSDs) considering the large number of unfavourable environmental and task-specific factors typical in this sector. Thus, it is important to have quantitative tools to support the assessment of the exposure to physical MSD risk factors. We employed wearable inertial sensors (ISs) to perform a real-world characterisation of static postures and repetitive movements involving the trunk and upper arms (UA), among 15 workers during 2 hours of their regular shifts.