Publications by authors named "M Gillstedt"

Background: Darier disease is a genodermatosis which manifests as hyperkeratotic papules and superficial erosions mainly in seborrheic skin areas. This retrospective registry-based cohort study aimed to estimate the association between Darier disease and skin cancer.

Results: Patients diagnosed with Darier disease were identified from the patient registry of Sahlgrenska University Hospital (Gothenburg, Sweden) in 2016-2020.

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Introduction: Short-term teledermoscopic monitoring helps to distinguish early melanomas from nevi. As the incidence of melanoma is increasing, there are several benefits of patients' taking their own dermoscopic images, but only a few previous studies have investigated the feasibility of this approach.

Objectives: To examine patients' ability to take evaluable dermoscopic images of atypical melanocytic lesions in need of short-term monitoring.

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Vitamin D plays an important role in psoriasis, but its involvement in pathogenesis remains unclear. This study aimed to evaluate vitamin D receptor (VDR) expression on peripheral blood mononuclear cells (PBMCs) in patients with psoriasis and healthy controls and to study the effects of the Etanercept treatment on VDR expression on PBMCs in patients with psoriasis. Twenty patients with moderate to severe psoriasis received treatment with Etanercept for 24 weeks.

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Article Synopsis
  • The gut microbiota is crucial for immune function, and its imbalance (dysbiosis) is associated with systemic inflammation, affecting conditions like psoriasis and depression.
  • This study investigates how switching psoriasis patients from TNF-α inhibitors to brodalumab affects their gut fungal microbiota, using fecal samples and advanced sequencing techniques.
  • Results indicate that while the dominant fungal group was Ascomycota, switching treatments did not significantly change fungal composition, despite clinical improvements, suggesting brodalumab may not impact fungal communities in psoriasis patients.
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