Publications by authors named "M Giletta"
Article Synopsis
- Childhood adversity (CA) is linked to higher risks of negative health outcomes, with differences in how various types of adversity affect brain structure during development.
- Recent research indicates that deprivation leads to slower decreases in cortical surface area in certain brain regions, while threat exposure results in increased surface area in areas related to socio-emotional processing as adolescents age.
- These findings suggest a need to reconsider how different forms of adversity affect brain development over time, highlighting the varying impacts on cognitive and emotional functions.
This study assessed interpersonal stressors (peer adversity and parental rejection) as predictors of adolescents' circulating inflammatory markers, while examining emotion regulation and parasympathetic nervous system activity (at rest, reactivity, and recovery) as potential protective moderators. Data were collected in a Belgian cohort of adolescents in 2017 (n=185, 51.4 % boys, 10-18 y) and 2018 (n=98), and included serum inflammatory markers (CRP, TNFα, IFNγ, IL-6, IL-8 and IL-10), peer adversity, parental rejection, emotion regulation and heart rate variability (RMSSD-HRV, at rest and in 2018 also in response to a Trier Social Stress Test).
View Article and Find Full Text PDFExamining systemic inflammation as a pathway linking peer victimization to depressive symptoms in adolescence.
J Child Psychol Psychiatry
October 2024
Background: Adolescents exposed to victimization are at an increased risk for a variety of adverse mental health outcomes, including depressive symptoms. Yet, the biological pathways underlying these associations remain poorly understood. Focusing on within-person processes, we examined whether low-grade systemic inflammation mediated the longitudinal associations between peer victimization and depressive symptoms in adolescence.
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